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[Association of polymorphism in alpha-adducin gene with antihypertensive effect of Hydrochlorothiazide].

Zhonghua xin xue guan bing za zhi - 1 Oct 2005

Wu Shou-ling, Li Dong-qing, Li Hong-fen, Yu Qing, Li Yun, Zhao Hai-yan

Abstract excerpt

OBJECTIVE: To explore the association between G614T single nuclear polymorphism (SNP) of the alpha-adducin gene and the antihypertensive effect of hydrochlorothiazide (HCTZ) in essential hypertensive (EH) patients. METHODS: Eight hundred twenty nine EH patients were given 12.5 mg HCTZ/d for six weeks. Alpha-adducin gene G614T SNP in the tenth exon was determined by PCR-RFLP in 754 patients with complete records....

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PMID: 16266470

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DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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