Article
Angiotensin I-converting enzyme gene polymorphism and drug response.
Clinical chemistry and laboratory medicine - 1 Sept 2000
Baudin B
Abstract excerpt
An insertion/deletion (I/D) polymorphism of the angiotensin I-converting enzyme (ACE) gene has been described in chromosome 17q23 of the human genome. Subjects with the genotype DD have markedly higher plasma ACE levels than those with genotype II; although ACE concentration in plasma is not rate-limiting for the production of angiotensin II, it has been suggested that the renin-angiotensin system may have an...
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