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Article

Determination of ABCB1 polymorphisms and haplotypes frequencies in a French population.

Fundamental & clinical pharmacology - 1 Aug 2007

Jeannesson Elise, Albertini Laetitia, Siest Gérard, Gomes Ana-Margarida, Ribeiro Vera, Aslanidis Charalampos, Schmitz Gerd, Visvikis-Siest Sophie

Abstract excerpt

The ATP-binding cassette (ABC) transporter ABCB1, or P-glycoprotein, is a transmembrane efflux pump well known for its implication in drug transport and chemoresistance. ABCB1 substrates include either drugs, such as antiretrovirals and immunomodulators, or physiological molecules like phospholipids. Pharmacogenetic analysis of ABCB1 polymorphisms, in addition to other xenobiotic metabolizing enzymes, might help...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17635180
DOI: 10.1111/j.1472-8206.2007.00507.x

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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