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Article

PIK3CA exon 20 mutation is independently associated with a poor prognosis in breast cancer patients.

Annals of surgical oncology - 1 Apr 2008

Lai Yuen-Liang, Mau Bey-Liing, Cheng Wen-Hsuan, Chen Han-Ming, Chiu Hsi-Hsiung, Tzen Chin-Yuan

Abstract excerpt

BACKGROUND: Prognostic factors that could select breast cancer patients with poor survival, and influence clinical trials of targeted therapy, are needed. However, the reported observations regarding the impact of PI3KCA mutation on breast cancers are controversial. METHODS: We analyzed exons 4, 7, 9, and 20 of PI3KCA on a series of 158 patients. Clinicopathological characteristics were correlated with the...

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Identifiers

PMID: 18183466
DOI: 10.1245/s10434-007-9751-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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