Article
PIK3CA mutations and their response to neoadjuvant treatment in early breast cancer: A systematic review and meta-analysis.
Thoracic cancer - 1 May 2018
Fan Hongwei, Li Chao, Xiang Qian, Xu Ling, Zhang Zhuo, Liu Qianxin, Zhang Tonttong, Zhou Ying, Zhao Xia, Cui Yimin
Abstract excerpt
BACKGROUND: PIK3CA mutations frequently occur in breast cancer patients. This study was conducted to evaluate the relationship between PIK3CA mutations and neoadjuvant treatment response and to analyze the clinical implications. METHODS: PubMed, Embase, and the Cochrane database were searched for relevant studies in September 2017. The pooled risk ratio (RR) was estimated using fixed effects or random effects...
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