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Article

PIK3CA mutation associates with improved outcome in breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2009

Kalinsky Kevin, Jacks Lindsay M, Heguy Adriana, Patil Sujata, Drobnjak Marija, Bhanot Umeshkumar K, Hedvat Cyrus V, Traina Tiffany A, Solit David, Gerald William, Moynahan Mary Ellen

Abstract excerpt

PURPOSE: In breast cancer, somatic mutations in the PIK3CA gene are common. The prognostic implication of these activating mutations remains uncertain as moderately sized studies have yielded variable outcomes. Our aim was to determine the prognostic implications of PIK3CA mutations in breast cancer. EXPERIMENTAL DESIGN: Archival formalin-fixed paraffin-embedded primary breast tumors, from 590 patients selected...

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Identifiers

PMID: 19671852
DOI: 10.1158/1078-0432.CCR-09-0632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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