Article
A statistical method for predicting classical HLA alleles from SNP data.
American journal of human genetics - 1 Jan 2008
Leslie Stephen, Donnelly Peter, McVean Gil
Abstract excerpt
Genetic variation at classical HLA alleles is a crucial determinant of transplant success and susceptibility to a large number of infectious and autoimmune diseases. However, large-scale studies involving classical type I and type II HLA alleles might be limited by the cost of allele-typing technologies. Although recent studies have shown that some common HLA alleles can be tagged with small numbers of markers,...
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