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Phenome-wide HLA association landscape of 235,000 Finnish biobank participants

2020-10-27

Abstract excerpt

The human leukocyte antigen (HLA) system is the single most important genetic susceptibility factor for many autoimmune diseases and immunological traits. However, in a range of clinical phenotypes the impact of HLA alleles or their combinations on the disease risk are not comprehensively understood. For systematic population-level analysis of HLA-phenotype associations we imputed the alleles of classical HLA gene...

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Literature Corpus work
87b86a58-0345-514d-8b2f-375b86a13143
DOI
10.1101/2020.10.26.20219899
Open publication

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Phenome-wide HLA association landscape of 235,000 Finnish biobank participantsDOI 10.1101/2020.10.26.20219899
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