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Article

Classical HLA allele and haplotype frequency estimates in US populations.

Human immunology - 1 Aug 2026

Gragert Loren, Madbouly Abeer, Bashyal Pradeep, Wadsworth Kim, Kempenich Jane, Bolon Yung-Tsi, Maiers Martin

Abstract excerpt

The human leukocyte antigen (HLA) system is the primary determinant of donor selection in allogeneic hematopoietic cell transplantation (HCT) and plays a central role in solid organ transplantation, immune-mediated disease studies, evolutionary population genetics, and immunotherapy. Large-scale sampling of registry participants reflecting major US ancestry groups allows for characterization of the complex...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42341485
DOI: 10.1016/j.humimm.2026.111792
PMCID: PMC13495449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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