Article
A deletion in the chemokine receptor 5 (CCR5) gene is associated with tickborne encephalitis.
The Journal of infectious diseases - 15 Jan 2008
Kindberg Elin, Mickiene Aukse, Ax Cecilia, Akerlind Britt, Vene Sirkka, Lindquist Lars, Lundkvist Ake, Svensson Lennart
Abstract excerpt
Tickborne encephalitis (TBE) virus infections can be asymptomatic or cause moderate to severe injuries of the central nervous system. Why some individuals develop severe disease is unknown, but a role for host genetic factors has been suggested. To investigate whether chemokine receptor CCR5 is associated with TBE, CCR5Delta32 genotyping was performed among Lithuanian patients with TBE (n=129) or with aseptic...
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