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Article

Polymorphisms in chemokine receptor 5 and Toll-like receptor 3 genes are risk factors for clinical tick-borne encephalitis in the Lithuanian population.

PloS one - 1 Jan 2014

Mickienė Auksė, Pakalnienė Jolita, Nordgren Johan, Carlsson Beatrice, Hagbom Marie, Svensson Lennart, Lindquist Lars

Abstract excerpt

BACKGROUND: Tick-borne encephalitis virus (TBEV) infections can be asymptomatic or cause moderate to severe injuries of the nervous system. We previously reported that a nonfunctional chemokine receptor 5 (CCR5) and a functional Toll-like receptor 3 (TLR3) predispose adults to clinical tick-borne encephalitis (TBE). This study expands our previous findings and further examines polymorphisms in CCR5 and TLR3 genes...

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Source

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Identifiers

PMID: 25226020
DOI: 10.1371/journal.pone.0106798
PMCID: PMC4165893

Genes

TLR3
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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