Article
The possible role of CCR5Δ32 mutation in Crimean-Congo hemorrhagic fever infection.
Journal of medical virology - 1 Oct 2017
Rustemoglu Aydin, Ekinci Duygu, Nursal Ayşe F, Barut Sener, Duygu Fazilet, Günal Özgür
Abstract excerpt
Crimean-Congo hemorrhagic fever infection (CCHF) is a viral zoonosis. The pathogenesis of this disease has not been established so far, however, cytokines account for its progression and outcome. The aim of the present study is to investigate the association between chemokine receptor 5 (CCR5) gene Δ32 mutation and pathogenity, severity, and mortality of CCHF. This case-control study included 133 CCHF patients...
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