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Article

Association of CCR5 delta32 deletion with early death in multiple sclerosis.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2000

Gade-Andavolu Radhika, Comings David E, MacMurray James, Rostamkhani Masoud, Cheng Li S-C, Tourtellotte Wallace W, Cone Lawrence A

Abstract excerpt

PURPOSE: The interaction between chemokines and their receptors is extremely important in controlling T cell migration into sites of CNS inflammation. Because trafficking of inflammatory T cells into the central nervous system (CNS) is a key player in the pathogenesis of multiple sclerosis (MS), we investigated the possible association of CCR5 delta32 deletion in this disorder. METHODS: DNA isolated from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15354329
DOI: 10.1097/01.gim.0000127274.45301.54

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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