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Article

CCR5 deficiency is a risk factor for early clinical manifestations of West Nile virus infection but not for viral transmission.

The Journal of infectious diseases - 15 Jan 2010

Lim Jean K, McDermott David H, Lisco Andrea, Foster Gregory A, Krysztof David, Follmann Dean, Stramer Susan L, Murphy Philip M

Abstract excerpt

BACKGROUND: West Nile virus (WNV) is a neurotropic flavivirus transmitted to humans by mosquito vectors. Homozygosity for CCR5Delta32, a complete loss-of-function mutation in CC chemokine receptor 5 (CCR5), has been previously associated with severe symptomatic WNV infection in patients who prese...

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Identifiers

PMID: 20025530
DOI: 10.1086/649426
PMCID: PMC2934858

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20025530-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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