Article
CCR5 chemokine receptor gene polymorphisms in ocular toxoplasmosis.
Acta tropica - 1 Feb 2018
de Faria Junior Geraldo M, Ayo Christiane M, de Oliveira Amanda P, Lopes Alessandro G, Frederico Fábio B, Silveira-Carvalho Aparecida P, Previato Mariana, Barbosa Amanda P, Murata Fernando H A, de Almeida Junior Gildásio Castello, Siqueira Rubens Camargo, de Mattos Luiz C, Brandão de Mattos Cinara C
Abstract excerpt
CC chemokine receptor type 5 (CCR5) is a chemokine receptor that influences the immune response to infectious and parasitic diseases. This study aimed to determine whether the CCR5Δ32 and CCR5 59029 A/G polymorphisms are associated with the development of ocular toxoplasmosis in humans. Patients with positive serology for Toxoplasma gondii were analyzed and grouped as 'with ocular toxoplasmosis' (G1: n=160) or...
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