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Article

Genetic polymorphisms of cyclooxygenase-2 and colorectal adenoma risk: the Self Defense Forces Health Study.

Cancer science - 1 Mar 2008

Ueda Naoyuki, Maehara Yoshihiko, Tajima Osamu, Tabata Shinji, Wakabayashi Keiji, Kono Suminori

Abstract excerpt

Cyclooxygenase (COX) is a key enzyme in the formation of prostaglandins, and an inducible isoform of COX, COX-2, has been implicated in colorectal carcinogenesis. This study investigated the relation of COX-2 polymorphisms (-1195G>A, -765G>C and 8160A>G) to colorectal adenomas in a case-control study of male officials in the Self Defense Forces (SDF). The study subjects were 455 cases of colorectal adenoma and...

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Source

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Identifiers

PMID: 18167131
DOI: 10.1111/j.1349-7006.2007.00711.x
PMCID: PMC11158649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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