Article
Cyclooxygenase-2 polymorphisms and susceptibility to colorectal cancer: a meta-analysis.
Yonsei medical journal - 1 Nov 2013
Wang Jun, Guo Xufeng, Zhang Jixiang, Song Jia, Ji Mengyao, Yu Shijie, Wang Jing, Cao Zhuo, Dong Weiguo
Abstract excerpt
PURPOSE: Four polymorphisms, -765G>C, -1195G>A, 8473T>C, and Val511Ala, in the cyclooxygenase-2 (COX-2) gene were identified to be associated with colorectal cancer (CRC) risk. However, the results are inconsistent. The objective of this meta-analysis was to evaluate the association between these four polymorphisms and the risk of CRC. MATERIALS AND METHODS: All eligible case-control studies published up to...
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