Article
COX-2 polymorphisms -765G-->C and -1195A-->G and colorectal cancer risk.
World journal of gastroenterology - 28 Sept 2009
Hoff Juliët H, te Morsche Rene H M, Roelofs Hennie M J, van der Logt Elise M J, Nagengast Fokko M, Peters Wilbert H M
Abstract excerpt
AIM: To determine the possible modulating effect of the COX-2 polymorphisms, -765G-->C and -1195A-->G, on the risk of colorectal cancer (CRC) in a Dutch population. METHODS: This case-control study includes 326 patients with CRC and 369 age- and gender-matched controls. Genotypes of the COX-2 polymorphisms -765G-->C and -1195A-->G were determined by polymerase chain reaction-based restriction fragment length...
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