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Article

COX-2 polymorphisms in patients with familial adenomatous polyposis.

Oncology research - 1 Jan 2009

Peters Wilbert H M, te Morsche Rene H M, Roelofs Hennie M J, Mathus-Vliegen Elisabeth M H, Berkhout Marloes, Nagengast Fokko M

Abstract excerpt

Cyclooxygenase-2 (COX-2) is an enzyme involved in the synthesis of prostaglandins and thromboxanes, which are regulators of biologic processes such as inflammation, cell proliferation, and angiogenesis. COX-2 has been found overexpressed in (pre)malignant tissues and may be relevant to cancer dev...

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Share to Adenomatous Polyposis Coli
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Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 19544971
DOI: 10.3727/096504009788428451

Genes

FAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19544971-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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