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Article

Genetic polymorphisms in the cyclooxygenase-1 and cyclooxygenase-2 genes and risk of colorectal adenoma.

International journal of colorectal disease - 1 Jun 2009

Gong Zhihong, Bostick Roberd M, Xie Dawen, Hurley Thomas G, Deng Zonglin, Dixon Dan A, Zhang Jinhui, Hebert James R

Abstract excerpt

PURPOSE: Cyclooxygenase (COX) enzymes, COX1 and COX2, are key in converting arachidonic acid (AA) into prostaglandins that have been associated with colorectal carcinogenesis. The aim of our study was to investigate associations of polymorphisms in COX genes, alone and in interaction with exposur...

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Source

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Identifiers

PMID: 19205707
DOI: 10.1007/s00384-009-0656-8
PMCID: PMC3461962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19205707-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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