Article
Cyclooxygenase 2 polymorphism and colorectal cancer: -765G>C variant modifies risk associated with smoking and body mass index.
World journal of gastroenterology - 21 Mar 2008
Xing Li-Li, Wang Zhen-Ning, Jiang Li, Zhang Yong, Xu Ying-Ying, Li Juan, Luo Yang, Zhang Xue
Abstract excerpt
AIM: To explore whether cyclooxygenase 2 (COX-2) -765G>C polymorphism is associated with susceptibility of colorectal cancer (CRC) and to evaluate the risk of colorectal cancer in relation to environmental exposures and polymorphism. METHODS: We conducted a case-control study of 137 patients with colorectal cancer and 199 cancer-free controls in northeast China. Multivariate logistic regression analysis was...
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