Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of complement factor H Y402H gene polymorphism with Alzheimer's disease.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2008

Zetterberg Madeleine, Landgren Sara, Andersson Malin E, Palmér Mona Seibt, Gustafson Deborah R, Skoog Ingmar, Minthon Lennart, Thelle Dag S, Wallin Anders, Bogdanovic Nenad, Andreasen Niels, Blennow Kaj, Zetterberg Henrik

Abstract excerpt

Alzheimer's disease (AD) and age-related macular degeneration (AMD) share several epidemiological and biochemical features. The present study aimed to assess the possible influence of the AMD-associated complement factor H (CFH) Y402H (1277T > C) polymorphism on the risk of AD. Caucasian subjects (n = 800) meeting the criteria for probable (n = 717) or definite (n = 83) AD and Caucasian non-demented controls (n =...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid beta-Peptides
Share to Apolipoprotein E4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Comorbidity

Share to Complement Factor H

Share to Histidine

Share to Macular Degeneration

Share to tau Proteins

Share to Tyrosine

Source

Identifiers

PMID: 18163432
DOI: 10.1002/ajmg.b.30668

Genes

CFH
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of complement factor H Y402H gene polymorphism with Alzheimer's disease.PMID 18163432Read ↗

Systematic review and meta-analysis of the association between complement factor H Y402H polymorphisms and age-related macular degeneration.Semantic proximity Read ↗

Association of complement factor H Y402H polymorphism and age-related macular degeneration in Brazilian patients.Semantic proximity Read ↗

Polymorphism p.402Y>H in the complement factor H protein is a risk factor for age related macular degeneration in an Italian population.Semantic proximity Read ↗

Association of the Y402H polymorphism in complement factor H gene and neovascular age-related macular degeneration in Chinese patients.Semantic proximity Read ↗

Complement factor H polymorphism in age-related macular degeneration.Semantic proximity Read ↗

Complement factor H Y402H variant and risk of age-related macular degeneration in Asians: a systematic review and meta-analysis.Semantic proximity Read ↗

CFH Variants Affect Structural and Functional Brain Changes and Genetic Risk of Alzheimer's Disease.Semantic proximity Read ↗

Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation.Semantic proximity Read ↗

Complement factor H and LOC387715 gene polymorphisms in a Greek population with age-related macular degeneration.Semantic proximity Read ↗

Complement gene single nucleotide polymorphisms and biomarker endophenotypes of Alzheimer's disease.Semantic proximity Read ↗

Association of CFH Y402H polymorphism with both forms of advanced age-related macular degeneration in Turkish patients.Semantic proximity Read ↗

Complement C7is a novel risk gene for Alzheimer's disease in Han ChineseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.