Article
Complement factor H and LOC387715 gene polymorphisms in a Greek population with age-related macular degeneration.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1 Nov 2009
Marioli Dimitra I, Pharmakakis Nikolaos, Deli Angeliki, Havvas Ioannis, Zarkadis Ioannis K
Abstract excerpt
BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of severe visual loss among people over 60 years old. The lack of a broadly effective treatment for AMD underscores the need to identify causative biomarkers that could serve as preventive targets. Thus far, two major susceptibility loci for AMD have been identified, CFH T1277C and LOC387715 G270T. The primary goal of the present study was to...
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