Article
Polymorphism p.402Y>H in the complement factor H protein is a risk factor for age related macular degeneration in an Italian population.
The British journal of ophthalmology - 1 Sept 2006
Simonelli F, Frisso G, Testa F, di Fiore R, Vitale D F, Manitto M P, Brancato R, Rinaldi E, Sacchetti L
Abstract excerpt
AIMS: To evaluate the complement factor H (CFH) p.402Y>H polymorphism as a risk factor in age related macular degeneration (AMD) in an Italian population. METHODS: 104 unrelated Italian AMD patients and 131 unrelated controls were screened for the CFH polymorphism p.402Y>H (c.1277 T>C), which has been associated with AMD. Retinography was obtained for patients and controls; the AMD diagnosis was confirmed by...
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