Article
Complement factor H polymorphism in age-related macular degeneration.
Ophthalmology - 1 Jul 2007
Narayanan Raja, Butani Virit, Boyer David S, Atilano Shari R, Resende Gilberto P, Kim David S, Chakrabarti Subhabrata, Kuppermann Baruch D, Khatibi Nikan, Chwa Marilyn, Nesburn Anthony B, Kenney M Cristina
Abstract excerpt
PURPOSE: To determine the association between complement factor H (CFH) polymorphism T1277C (tyrosine-402 --> histidine-402) and phenotypic variations of age-related macular degeneration (AMD). DESIGN: Cross-sectional observational study. PARTICIPANTS: Subjects with dry or wet AMD and a control population consisting of age-matched non-AMD subjects from 2 clinical facilities examined during the period January 1,...
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