Article
Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation.
Neurobiology of aging - 1 Aug 2012
Proitsi Petroula, Lupton Michelle K, Dudbridge Frank, Tsolaki Magda, Hamilton Gillian, Daniilidou Makrina, Pritchard Megan, Lord Kathryn, Martin Belinda M, Johnson Janet, Craig David, Todd Stephen, McGuinness Bernadette, Hollingworth Paul, Harold Denise, Kloszewska Iwona, Soininen Hilkka, Mecocci Patrizia, Velas Bruno, Gill Michael, Lawlor Brian, Rubinsztein David C, Brayne Carol, Passmore Peter A, Williams Julie, Lovestone Simon, Powell John F
Abstract excerpt
Alzheimer's disease (AD) and age-related macular degeneration (AMD) are both neurodegenerative disorders which share common pathological and biochemical features of the complement pathway. The aim of this study was to investigate whether there is an association between well replicated AMD genetic...
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