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Article

Association of the Y402H polymorphism in complement factor H gene and neovascular age-related macular degeneration in Chinese patients.

Investigative ophthalmology & visual science - 1 Aug 2006

Lau Ling-Ing, Chen Shih-Jen, Cheng Ching-Yu, Yen May-Yung, Lee Fenq-Lih, Lin Ming-Wei, Hsu Wen-Ming, Wei Yau-Huei

Abstract excerpt

PURPOSE: Age-related macular degeneration (AMD), with its complex traits and multiple risk factors, is the leading cause of blindness in the elderly. A strong association between a coding variant, Y402H, in the complement factor H gene (CFH) and AMD has been recently identified in white patients. This study was conducted to investigate the association between the Y402H polymorphism in CFH and neovascular AMD in...

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Source

Identifiers

PMID: 16877387
DOI: 10.1167/iovs.05-1532

Genes

CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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