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Article

Single-molecule tracking of mRNA exiting from RNA polymerase II.

Proceedings of the National Academy of Sciences of the United States of America - 8 Jan 2008

Andrecka Joanna, Lewis Robert, Brückner Florian, Lehmann Elisabeth, Cramer Patrick, Michaelis Jens

Abstract excerpt

Single-pair fluorescence resonance energy transfer was used to track RNA exiting from RNA polymerase II (Pol II) in elongation complexes. Measuring the distance between the RNA 5' end and three known locations within the elongation complex allows us determine its position by means of triangulation. RNA leaves the polymerase active center cleft via the previously proposed exit tunnel and then disengages from the...

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Identifiers

PMID: 18162559
DOI: 10.1073/pnas.0703815105
PMCID: PMC2224174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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