Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recipient NOD2/CARD15 variants: a novel independent risk factor for the development of bronchiolitis obliterans after allogeneic stem cell transplantation.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Jan 2008

Hildebrandt Gerhard C, Granell Miguell, Urbano-Ispizua Alvaro, Wolff Daniel, Hertenstein Bernd, Greinix Hildegard T, Brenmoehl Julia, Schulz Christian, Dickinson Anne M, Hahn Joachim, Rogler Gerhard, Andreesen Reinhard, Holler Ernst

Abstract excerpt

Bronchiolitis obliterans (BO) is a serious complication after allogeneic stem cell transplantation. We hypothesized that single nucleotide polymorphisms (SNPs) of the NOD2/CARD15 gene (=NOD2/CARD15 variants) contribute to changes in host defense and subsequent alloreaction, leading to BO. We analyzed 427 donor-recipient pairs for the association of NOD2/CARD15 variants (SNP8 [Arg702Trp], SNP12 [Gly908Arg], and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Graft vs Host Disease

Share to Hematopoietic Stem Cell Transplantation

Share to Nod2 Signaling Adaptor Protein

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to Transplantation, Homologous

Source

Identifiers

PMID: 18158963
DOI: 10.1016/j.bbmt.2007.09.009

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recipient NOD2/CARD15 variants: a novel independent risk factor for the development of bronchiolitis obliterans after allogeneic stem cell transplantation.PMID 18158963Read ↗

Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation.Semantic proximity Read ↗

Effect of NOD2/CARD15 variants in T-cell depleted allogeneic stem cell transplantation.Semantic proximity Read ↗

Single nucleotide polymorphisms in the NOD2/CARD15 gene are associated with an increased risk of relapse and death for patients with acute leukemia after hematopoietic stem-cell transplantation with unrelated donors.Semantic proximity Read ↗

The role of genetic variants of NOD2/CARD15, a receptor of the innate immune system, in GvHD and complications following related and unrelated donor haematopoietic stem cell transplantation.Semantic proximity Read ↗

Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontamination.Semantic proximity Read ↗

Polymorphisms within epithelial receptors: NOD2/CARD15.Semantic proximity Read ↗

Mutations in innate immune system NOD2/CARD 15 and TLR-4 (Thr399Ile) genes influence the risk for severe acute graft-versus-host disease in patients who underwent an allogeneic transplantation.Semantic proximity Read ↗

The role of NOD1/CARD4 and NOD2/CARD15 genetic variations in lung cancer risk.Semantic proximity Read ↗

NOD2/CARD15 variants are not a risk factor for clinical outcome after nonmyeloablative allogeneic stem cell transplantation.Semantic proximity Read ↗

Role of NOD1/CARD4 and NOD2/CARD15 gene polymorphisms in cancer etiology.Semantic proximity Read ↗

No impact of NOD2/CARD15 on outcome after SCT.Semantic proximity Read ↗

Genetic variants in the NOD2/CARD15 gene are associated with early mortality in sepsis patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.