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Article

Role of NOD1/CARD4 and NOD2/CARD15 gene polymorphisms in cancer etiology.

Human immunology - 1 Oct 2011

Kutikhin Anton G

Abstract excerpt

NOD1/CARD4 and NOD2/CARD15 are members of Nod-like receptor family. They are located in cytosol, bind bacterial and viral ligands and play a key role in realization of innate and adaptive immune response, apoptosis, autophagy, and reactive oxygen species generation. Polymorphisms in NOD1/CARD4 and NOD2/CARD15 genes may shift balance between pro- and anti-inflammatory cytokines, modulating the risk of infection,...

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Source

Identifiers

PMID: 21745515
DOI: 10.1016/j.humimm.2011.06.003

Genes

NOD1
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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