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Article

No impact of NOD2/CARD15 on outcome after SCT.

Bone marrow transplantation - 1 Jun 2008

Sairafi D, Uzunel M, Remberger M, Ringdén O, Mattsson J

Abstract excerpt

Recent studies have pointed towards an association between certain single nucleotide polymorphisms (SNPs) in the NOD2/CARD15 gene, and negative outcome of Allo-SCT. In this study, 198 patients and their corresponding donors were analyzed retrospectively for the occurrence of NOD2/CARD15 mutations to evaluate the impact on clinical results after Allo-SCT. In all, 7.6% of the patients and 11% of the donors were...

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Source

Identifiers

PMID: 18317454
DOI: 10.1038/bmt.2008.9

Genes

SCT
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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No impact of NOD2/CARD15 on outcome after SCT.PMID 18317454Read ↗

Effect of NOD2/CARD15 variants in T-cell depleted allogeneic stem cell transplantation.Semantic proximity Read ↗

The role of genetic variants of NOD2/CARD15, a receptor of the innate immune system, in GvHD and complications following related and unrelated donor haematopoietic stem cell transplantation.Semantic proximity Read ↗

NOD2/CARD15 variants are not a risk factor for clinical outcome after nonmyeloablative allogeneic stem cell transplantation.Semantic proximity Read ↗

Single nucleotide polymorphisms in the NOD2/CARD15 gene are associated with an increased risk of relapse and death for patients with acute leukemia after hematopoietic stem-cell transplantation with unrelated donors.Semantic proximity Read ↗

Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontamination.Semantic proximity Read ↗

Recipient NOD2/CARD15 variants: a novel independent risk factor for the development of bronchiolitis obliterans after allogeneic stem cell transplantation.Semantic proximity Read ↗

Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation.Semantic proximity Read ↗

Mutations in innate immune system NOD2/CARD 15 and TLR-4 (Thr399Ile) genes influence the risk for severe acute graft-versus-host disease in patients who underwent an allogeneic transplantation.Semantic proximity Read ↗

Insufficient evidence for association of NOD2/CARD15 or other inflammatory bowel disease-associated markers on GVHD incidence or other adverse outcomes in T-replete, unrelated donor transplantation.Semantic proximity Read ↗

Polymorphism of interleukin-23 receptor gene but not of NOD2/CARD15 is associated with graft-versus-host disease after hematopoietic stem cell transplantation in children.Semantic proximity Read ↗

No evidence of association between NOD2/CARD15 gene polymorphism and atherosclerotic events after renal transplantation.Semantic proximity Read ↗

NOD2 polymorphisms predict severe acute graft-versus-host and treatment-related mortality in T-cell-depleted haematopoietic stem cell transplantation.Semantic proximity Read ↗

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