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Article

The role of NOD1/CARD4 and NOD2/CARD15 genetic variations in lung cancer risk.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Oct 2015

Ozbayer Cansu, Kurt Hulyam, Bayramoglu Aysegul, Gunes Hasan Veysi, Metintas Muzaffer, Degirmenci İrfan, Oner Kevser Setenay

Abstract excerpt

BACKGROUND AND AIM: NOD1/CARD4 and NOD2/CARD15 are members of the Nod-like receptor (NLR) family, and they contain a caspase recruitment domain (CARD). NLRs are located in the cytosol where they bind bacterial and viral ligands and play a key role in the innate and adaptive immune response, apoptosis, autophagy, and reactive oxygen species generation. NLR gene polymorphisms may shift the balance between pro- and...

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Source

Identifiers

PMID: 26238283
DOI: 10.1007/s00011-015-0859-0

Genes

NOD1
NOD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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