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Article

Genetic variants in the NOD2/CARD15 gene are associated with early mortality in sepsis patients.

Intensive care medicine - 1 Sept 2007

Brenmoehl Julia, Herfarth Hans, Glück Thomas, Audebert Franz, Barlage Stefan, Schmitz Gerd, Froehlich Dieter, Schreiber Stefan, Hampe Jochen, Schölmerich Jürgen, Holler Ernst, Rogler Gerhard

Abstract excerpt

OBJECTIVE: Genetic variants in the NOD2/CARD15 gene resulting in a diminished capacity to activate NF-kappaB in response to bacterial cell wall products have been associated with Crohn's disease (CD). Recently, we found an association between the variant Leu1007fsinsC of the NOD2/CARD15 gene (SNP...

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Source

Identifiers

PMID: 17558494
DOI: 10.1007/s00134-007-0722-z

Genes

NOD2
SRM
SCT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17558494-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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