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Article

Polymorphisms within epithelial receptors: NOD2/CARD15.

Methods in molecular medicine - 1 Jan 2007

Brenmoehl Julia, Holler Ernst, Rogler Gerhard

Abstract excerpt

Genetic risk assessment in the setting of allogeneic stem cell transplantation is one of the major goals to optimise future prophylaxis and treatment of patients: our group has focused on analysis of single-nucleotide polymorphisms (SNPs) within the intracytoplasmatic receptor NOD2/CARD15, which recognizes the bacterial cell wall compound muramyl-dipeptide and induces nuclear factor-kappaB-mediated inflammation....

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Source

Identifiers

PMID: 17666747
DOI: 10.1007/978-1-59745-223-6_9

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Polymorphisms within epithelial receptors: NOD2/CARD15.PMID 17666747Read ↗

Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation.Semantic proximity Read ↗

The role of genetic variants of NOD2/CARD15, a receptor of the innate immune system, in GvHD and complications following related and unrelated donor haematopoietic stem cell transplantation.Semantic proximity Read ↗

Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontamination.Semantic proximity Read ↗

Can NOD2/CARD15 mutations predict intestinal graft-versus-host disease and aid our understanding of Crohn's disease?Semantic proximity Read ↗

Genetic variants in the NOD2/CARD15 gene are associated with early mortality in sepsis patients.Semantic proximity Read ↗

Role of NOD1/CARD4 and NOD2/CARD15 gene polymorphisms in cancer etiology.Semantic proximity Read ↗

Single nucleotide polymorphisms in the NOD2/CARD15 gene are associated with an increased risk of relapse and death for patients with acute leukemia after hematopoietic stem-cell transplantation with unrelated donors.Semantic proximity Read ↗

NOD2/CARD15 single nucleotide polymorphism 13 (3020insC) is associated with risk of sepsis and single nucleotide polymorphism 8 (2104C>T) with herpes viruses reactivation in patients after allogeneic hematopoietic stem cell transplantation.Semantic proximity Read ↗

NOD2/CARD15 disease associations other than Crohn's disease.Semantic proximity Read ↗

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Novel CARD15/NOD2 mutations in Finnish patients with Crohn's disease and their relation to phenotypic variation in vitro and in vivo.Semantic proximity Read ↗

NOD2, an intracellular innate immune sensor involved in host defense and Crohn's disease.Semantic proximity Read ↗

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