Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation.

Blood - 1 Aug 2004

Holler Ernst, Rogler Gerhard, Herfarth Hans, Brenmoehl Julia, Wild Peter Johannes, Hahn Joachim, Eissner Günther, Schölmerich Jürgen, Andreesen Reinhard

Abstract excerpt

Single nucleotide polymorphisms (SNPs) of the NOD2/CARD15 gene resulting in a diminished nuclear factor-kappaB (NF-kappaB) response to bacterial cell wall products have been associated with an increased incidence of Crohn disease. To assess a possible contribution of NOD2/CARD15 mutations to graf...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier Proteins
Share to Graft vs Host Disease
Share to Intracellular Signaling Peptides and Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nod2 Signaling Adaptor Protein

Share to Stem Cell Transplantation

Share to Survival Analysis

Share to Time Factors

Share to Transplantation, Homologous

Source

Identifiers

PMID: 15090455
DOI: 10.1182/blood-2003-10-3543

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15090455-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation.PMID 15090455Read ↗

Polymorphisms within epithelial receptors: NOD2/CARD15.Semantic proximity Read ↗

Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontamination.Semantic proximity Read ↗

Single nucleotide polymorphisms in the NOD2/CARD15 gene are associated with an increased risk of relapse and death for patients with acute leukemia after hematopoietic stem-cell transplantation with unrelated donors.Semantic proximity Read ↗

The role of genetic variants of NOD2/CARD15, a receptor of the innate immune system, in GvHD and complications following related and unrelated donor haematopoietic stem cell transplantation.Semantic proximity Read ↗

Effect of NOD2/CARD15 variants in T-cell depleted allogeneic stem cell transplantation.Semantic proximity Read ↗

Recipient NOD2/CARD15 variants: a novel independent risk factor for the development of bronchiolitis obliterans after allogeneic stem cell transplantation.Semantic proximity Read ↗

Genetic variants in the NOD2/CARD15 gene are associated with early mortality in sepsis patients.Semantic proximity Read ↗

Functional consequences of NOD2 (CARD15) mutations.Semantic proximity Read ↗

Mutations in innate immune system NOD2/CARD 15 and TLR-4 (Thr399Ile) genes influence the risk for severe acute graft-versus-host disease in patients who underwent an allogeneic transplantation.Semantic proximity Read ↗

NOD2/CARD15 disease associations other than Crohn's disease.Semantic proximity Read ↗

NOD2/CARD15 single nucleotide polymorphism 13 (3020insC) is associated with risk of sepsis and single nucleotide polymorphism 8 (2104C>T) with herpes viruses reactivation in patients after allogeneic hematopoietic stem cell transplantation.Semantic proximity Read ↗

Can NOD2/CARD15 mutations predict intestinal graft-versus-host disease and aid our understanding of Crohn's disease?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.