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Article

Notch2 is required for maintaining sustentacular cell function in the adult mouse main olfactory epithelium.

Developmental biology - 1 Feb 2008

Rodriguez Steve, Sickles Heather M, Deleonardis Chris, Alcaraz Ana, Gridley Thomas, Lin David M

Abstract excerpt

Notch receptors are expressed in neurons and glia in the adult nervous system, but why this expression persists is not well-understood. Here we examine the role of the Notch pathway in the postnatal mouse main olfactory system, and show evidence consistent with a model where Notch2 is required for maintaining sustentacular cell function. In the absence of Notch2, the laminar nature of these glial-like cells is...

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Identifiers

PMID: 18155189
DOI: 10.1016/j.ydbio.2007.10.056
PMCID: PMC2374763

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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