Article
Megane/Heslike is required for normal GABAergic differentiation in the mouse superior colliculus.
Development (Cambridge, England) - 1 Oct 2006
Guimera Jordi, Weisenhorn Daniela Vogt, Wurst Wolfgang
Abstract excerpt
The mouse Mgn protein (Helt) is structurally related to the neurogenic Drosophila hairy and Enhancer of split [h/E(spl)] proteins, but its unique structural properties distinguish it from other members of the family. Mgn expression shows a spatiotemporal correlation with GABAergic markers in several brain regions. We report here that homozygous Mgn-null mice die between the second and the fifth postnatal week of...
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