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Article

The homeobox gene Gsh2 is required for retinoid production in the embryonic mouse telencephalon.

Development (Cambridge, England) - 1 Aug 2004

Waclaw Ronald R, Wang Bei, Campbell Kenneth

Abstract excerpt

We have examined the role of the homeobox gene Gsh2 in retinoid production and signaling within the ventral telencephalon of mouse embryos. Gsh2 mutants exhibit altered ventral telencephalic development, including a smaller striatum with fewer DARPP-32 neurons than wild types. We show that the expression of the retinoic acid (RA) synthesis enzyme, retinaldehyde dehydrogenase 3 (Raldh3, also known as Aldh1a3), is...

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PMID: 15269172
DOI: 10.1242/dev.01272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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