Patterns of Jagged1, Jagged2, Delta‐like 1 and Delta‐like 3 expression during late embryonic and postnatal brain development suggest multiple functional roles in progenitors and differentiated cells

Abstract excerpt

The Notch-DSL signaling system, consisting of multiple receptors and ligands, inhibits neurogenesis and promotes gliogenesis during embryonic development, but the specific function of the various ligands and receptors at later developmental stages are unknown. Here, we examined the expression pattern of four Delta, Serrate and Lag-2 (DSL) ligands, Jagged1, Jagged2, Delta-like1 (Dl1) and Delta-like 3 (Dl3), in...

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