Article
Canonical Notch signaling plays an instructive role in auditory supporting cell development.
Scientific reports - 20 Jan 2016
Campbell Dean P, Chrysostomou Elena, Doetzlhofer Angelika
Abstract excerpt
The auditory sensory epithelium, composed of mechano-sensory hair cells (HCs) and highly specialized glial-like supporting cells (SCs), is critical for our ability to detect sound. SCs provide structural and functional support to HCs and play an essential role in cochlear development, homeostasis and repair. Despite their importance, however, surprisingly little is known about the molecular mechanisms guiding SC...
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