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Article

Predicting survival in head and neck squamous cell carcinoma from TP53 mutation.

Human genetics - 1 May 2015

Masica David L, Li Shuli, Douville Christopher, Manola Judith, Ferris Robert L, Burtness Barbara, Forastiere Arlene A, Koch Wayne M, Chung Christine H, Karchin Rachel

Abstract excerpt

For TP53-mutated head and neck squamous cell carcinomas (HNSCCs), the codon and specific amino acid sequence change resulting from a patient's mutation can be prognostic. Thus, developing a framework to predict patient survival for specific mutations in TP53 would be valuable. There are many bioinformatics and functional methods for predicting the phenotypic impact of genetic variation, but their overall clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25108461
DOI: 10.1007/s00439-014-1470-0
PMCID: PMC4324386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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