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Article

Targeting the DNA Damage Response in OSCC with TP53 Mutations.

Journal of dental research - 1 Jun 2018

Lindemann A, Takahashi H, Patel A A, Osman A A, Myers J N

Abstract excerpt

Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer worldwide and in the United States. OSCC remains a major cause of morbidity and mortality in patients with head and neck cancers. Tobacco and alcohol consumption alone or with chewing betel nut are potential risk factors contributing to the high prevalence of OSCC. Multimodality therapies, including surgery, chemotherapy, biologic therapy,...

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Share to Cancer-related Molecular Pathways
Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29489434
DOI: 10.1177/0022034518759068
PMCID: PMC5960880

Genes

ATM
ATR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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