No association of the CARD8 (TUCAN) c.30T>A (p.C10X) variant with Crohn's disease: a study in 3 independent European cohorts.

doi:10.1002/ibd.20337

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

No association of the CARD8 (TUCAN) c.30T>A (p.C10X) variant with Crohn's disease: a study in 3 independent European cohorts.

Inflammatory bowel diseases - 1 Mar 2008

Büning Carsten, Schmidt Hartmut H-J, Molnár Tamás, Drenth Joost Ph, Fiedler Thomas, Gentz Enno, Todorov Theodor, Baumgart Daniel C, Sturm Andreas, Nagy Ferenc, Lonovics János, de Jong Dirk J, Landt Olfert, Kage Andreas, Nickel Renate, Büttner Janine, Lochs Herbert, Witt Heiko

Abstract excerpt

BACKGROUND: A recent study reported that the c.30T>A (p.Cys10Ter; rs2043211) variant, in the CARD8 (TUCAN) gene, is associated with Crohn's disease (CD). The aim of this study was to analyze the frequency of p.C10X in 3 independent European (IBD) cohorts from Germany, Hungary, and the Netherlands...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CARD Signaling Adaptor Proteins

Share to Crohn Disease

Share to Germany

Share to Hungary

Share to Neoplasm Proteins

Share to Netherlands

Share to Nod2 Signaling Adaptor Protein

Source

Open in PubMed

Identifiers

PMID: 18092344
DOI: 10.1002/ibd.20337

Genes

CARD8
NOD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18092344-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

No association of the CARD8 (TUCAN) c.30T>A (p.C10X) variant with Crohn's disease: a study in 3 independent European cohorts.PMID 18092344Read ↗

TUCAN (CARD8) genetic variants and inflammatory bowel disease.Semantic proximity Read ↗

Novel isoforms of the CARD8 (TUCAN) gene evade a nonsense mutation.Semantic proximity Read ↗

Card15 and Crohn's disease: healthy homozygous carriers of the 3020insC frameshift mutation.Semantic proximity Read ↗

Distribution of common CARD15 variants in patients with sporadic Crohn's disease: cases from Turkey.Semantic proximity Read ↗

Frequency of CARD15 polymorphisms in patients with Crohn's disease from Toledo, Spain: genotype-phenotype correlation.Semantic proximity Read ↗

NOD2c.3019-3020insC AND c.2104C>T GENE VARIANTS AMONG PATIENTS FROM WESTERN UKRAINE WITH CROHN'S DISEASE AND COLORECTAL CANCER.Semantic proximity Read ↗

Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn’s diseaseSemantic proximity Read ↗

Variants of OCTN1-2 cation transporter genes are associated with both Crohn's disease and ulcerative colitis.Semantic proximity Read ↗

Genetic variants in CARD8 but not in NLRP3 are associated with ankylosing spondylitis.Semantic proximity Read ↗

Analysis of Crohn's disease-related CARD15 polymorphisms in Spanish patients with idiopathic uveitis.Semantic proximity Read ↗

[Susceptibility genetic variants in Hungarian morbus Crohn and ulcerative colitis patients].Semantic proximity Read ↗

CARD8 p.C10X polymorphism is associated with inflammatory activity in early rheumatoid arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.