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NOD2c.3019-3020insC AND c.2104C>T GENE VARIANTS AMONG PATIENTS FROM WESTERN UKRAINE WITH CROHN'S DISEASE AND COLORECTAL CANCER.

Experimental oncology - 1 May 2022

Lozynska L, Pinyazhko R, Lozynska M, Plawski A, Makukh H, Lukavetskyy O, Grzegotsky M, Pinyazhko O

Abstract excerpt

AIM: To determine the frequency of NOD2 gene c.3019-3020insC (rs5743293) and c.2104C>T (rs2066844) allelic variants in the patients with Crohn's disease (CD), colorectal cancer (CRC) and in the control groups and to study the association of these mutations with the onset time of the diseases, gender and surgical interventions. MATERIALS AND METHODS: The diagnoses of CD and CRC were established based on standard...

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PMID: 35548966
DOI: 10.32471/exp-oncology.2312-8852.vol-44-no-1.17305

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