Article
Analysis of Crohn's disease-related CARD15 polymorphisms in Spanish patients with idiopathic uveitis.
Disease markers - 1 Jan 2008
Rodríguez-Pérez N, Aguinaga-Barrilero A, Gorroño-Echebarría Marina B, Pérez-Blas Mercedes, Martín-Villa J M
Abstract excerpt
We wished to analyse the frequency of Crohn's disease-linked CARD15 polymorphisms (P268S, R702W, G908R and 1007fs) in a group of Spanish patients with idiopathic uveitis. To this aim, DNA samples were obtained from 111 unrelated patients. P268S, R702W and G908R polymorphisms were detected using TaqMan Genotyping kits (Applied Biosystems), and the 1007fs variation by direct DNA sequencing. Control group consisted...
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