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Article

Novel isoforms of the CARD8 (TUCAN) gene evade a nonsense mutation.

European journal of human genetics : EJHG - 1 May 2008

Bagnall Richard D, Roberts Roland G, Mirza Muddassar M, Torigoe Toshihiko, Prescott Natalie J, Mathew Christopher G

Abstract excerpt

CARD8 (TUCAN) is implicated in the regulation of apoptosis and inflammation, and is a positional and functional candidate gene for inflammatory bowel disease (IBD). Recent investigations have reported conflicting results of association between a CARD8 nonsynonymous SNP, rs2043211, and IBD. SNP rs2043211 results in an A>T transversion in the CARD8 template strand, which introduces a stop codon polymorphism...

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Source

Identifiers

PMID: 18212821
DOI: 10.1038/sj.ejhg.5201996

Genes

CARD8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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