Article
Constitutive nitric oxide synthase gene polymorphisms and house dust mite respiratory allergy in an Algerian patient group.
Tissue antigens - 1 Feb 2008
Djidjik R, Ghaffor M, Brun M, Gharnaout M, Salah S S, Boukouaci W, Djidjik H, Benyounes A, Koumaravelou K, Krishnamoorthy R, Abbadi M C, Charron D, Tamouza R
Abstract excerpt
Genetic polymorphisms in neuronal nitric oxide synthase (NOS1) and calmodulin-dependent endothelial NOS (NOS3) genes are known to influence the course of allergic respiratory disorders. We investigated the role of NOS1 -84 G-->A and NOS3 -786 T-->C, 894 G-->T and 27 base pair (bp) repeat polymorphisms in 125 patients suffering from asthma and/or rhinitis and monosensitized against Dermatophagoides pteronyssinus...
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