Male-biased association of endothelial nitric oxide synthase Asp298Glu substitution (NOS3-c.894G/T) with asthma risk and severity.

doi:10.1080/02770903.2023.2196689

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Article

Male-biased association of endothelial nitric oxide synthase Asp298Glu substitution (NOS3-c.894G/T) with asthma risk and severity.

The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Oct 2023

Aftabi Younes, Amiri-Sadeghan Amir, Gilani Neda, Zahedi Tahereh, Khodayari Mohamad Taghi, Faramarzi Elnaz, Seyedrezazadeh Ensiyeh, Ansarin Khalil

Abstract excerpt

OBJECTIVE: The nitric-oxide pathway plays a crucial role in the pathogeneses of asthma and NOS3-encoded endothelial nitric oxide synthase is one of the main components of the pathway. Variants of NOS3 are known to contribute to asthma development and pathophysiology. METHODS: We investigated the association of NOS3-c.894G/T (rs1799983) with asthma risk and severity by studying frequencies of its genotypes and...

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PMID: 36971059
DOI: 10.1080/02770903.2023.2196689

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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