Article
Prevalence of endothelial nitric oxide synthase gene polymorphisms in patients with atopic asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Aug 2002
Hollá L I, Bucková D, Kuhrová V, Stejskalová A, Francová H, Znojil V, Vácha J
Abstract excerpt
BACKGROUND: Asthma is a common multifactorial disease, the aetiology of which is attributable to both environmental and genetic factors. The endothelial nitric oxide synthase (NOS3) gene has been implicated in asthma pathogenesis. OBJECTIVE: This study investigated associations of 27 base-pair tandem repeat polymorphism in intron 4 and the Glu298Asp (G894T) variant of the NOS3 gene with atopic asthma in a Czech...
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