Article
Nitric oxide synthase polymorphisms and asthma phenotypes in Chinese children.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Oct 2005
Leung T F, Liu E K H, Tang N L S, Ko F W S, Li C Y, Lam C W K, Wong G W K
Abstract excerpt
BACKGROUND: Nitric oxide (NO) is a key factor for balancing T-helper type 1/T-helper type 2 immunity. Single nucleotide polymorphisms (SNPs) in nitric oxide synthase (NOS) genes have been associated with atopy and exhaled NO concentrations in Caucasians. We investigated the association between asthma traits and genetic polymorphisms in neuronal NO synthase (NOS1) and endothelial NO synthase (NOS3) in Chinese...
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